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CRE Insights Blog
Last updated on Feb 19, 2023
3 min read
by Jeff Hamann

Office-to-Lab Conversions Pick Up, Despite Costs

Strong rent growth amid soaring demand is bringing investors large and small into the life science sector.

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In this article:
  1. High Demand for Life Science Space Drives Office-to-Lab Conversions
  2. Why Are Life Science Assets Expensive to Build?
  3. The Rental Upside
  4. Related Questions
  5. Get Financing

High Demand for Life Science Space Drives Office-to-Lab Conversions

Lab space is in high demand across America, but there simply isn’t enough space to meet users’ needs. At the end of 2021, vacancy in the life sciences sector of the top three metros — Boston, San Diego, and the San Francisco Bay Area — fell beneath 4%, according to a first-quarter report from CBRE.

Image by CDC from Unsplash.

Investors have been quick to get involved in the sector. Last year, total investment volume hit $18.4 billion, according to a year-end report from Newmark, up from $11.2 billion in 2020 and the highest single year of transactions on record, even registering a 17.2% increase compared to the previous peak in 2016 of $15.7 billion.

Developers are looking to address the acute shortage of life sciences space in two main ways: ground-up development and conversion. In the fourth quarter last year, just shy of 29 million square feet of life science space was under construction. The bulk of it came from new, ground-up developments, but an increasing amount of existing space — usually office — is being converted to meet tenant needs. CBRE data shows that research and development conversions increased by 49% between the first and fourth quarters last year, based on square footage under construction.

Why Are Life Science Assets Expensive to Build?

While it may be logical that lab and life science buildings are more costly to construct or convert than most if not all asset types, which specific characteristics of these properties drives the pricing the most?

The answer is, many different characteristics, and it truly depends on the asset — and the type of tenant it is looking to attract. Some of the characteristics that are among the most expensive include:

  • Emergency power generators

  • Additional plumbing

  • Improved HVAC systems

  • Higher floor load capacities (compared to office space)

  • Increased security requirements

These can all add significant costs, and as a result, new lab space can cost up to $1,200 per square foot to construct, with an additional $600 per square foot for interior improvements. This is far greater than the high end of the office spectrum in those same top three markets, where office construction costs range up to $850 per square foot for a new building, plus an additional $110 to $315 per square foot for tenant improvements.

The Rental Upside

Regardless of the construction or conversion costs, there’s a significant financial incentive for investors and developers to get involved in the life sciences sector. Rent growth has skyrocketed and looks poised for future elevation: A report from Colliers projects significant increases in nearly every major life science market in the U.S.

This can be seen at the market level in virtually all metros with a significant inventory. Take San Diego, one of the country’s largest life science markets. Between the fourth quarter of 2021 and the first quarter of this year, rents grew by an incredible 7.2% — and, given the lack of available space marketwide, will likely climb even further as the year progresses.

Also, unlike office, where remote work is often a viable option, most functions within a lab cannot be shifted to a home setup, instead requiring sophisticated technology and devices on-site. Thus, life science space is both necessary and expensive. Thus, even despite the high costs of conversion, many investors, both large and small, are looking to get into the space in search of strong, sustainable long-term yields.

Related Questions

What are the benefits of office-to-lab conversions?

The benefits of office-to-lab conversions are numerous. First, there is a significant financial incentive for investors and developers to get involved in the life sciences sector. Rent growth has skyrocketed and looks poised for future elevation, according to a report from Colliers. This can be seen at the market level in virtually all metros with a significant inventory. For example, between the fourth quarter of 2021 and the first quarter of this year, rents in San Diego grew by an incredible 7.2%.

Also, unlike office, where remote work is often a viable option, most functions within a lab cannot be shifted to a home setup, instead requiring sophisticated technology and devices on-site. Thus, life science space is both necessary and expensive. This means that even despite the high costs of conversion, many investors, both large and small, are looking to get into the space in search of strong, sustainable long-term yields.

What are the costs associated with office-to-lab conversions?

The costs associated with office-to-lab conversions can be significant. According to a report from Colliers, new lab space can cost up to $1,200 per square foot to construct, with an additional $600 per square foot for interior improvements. This is far greater than the high end of the office spectrum in those same top three markets, where office construction costs range up to $850 per square foot for a new building, plus an additional $110 to $315 per square foot for tenant improvements.

What are the most common types of office-to-lab conversions?

The most common types of office-to-lab conversions are those that involve adding emergency power generators, additional plumbing, improved HVAC systems, higher floor load capacities, and increased security requirements. These features can add significant costs to the conversion process, with new lab space costing up to $1,200 per square foot to construct, plus an additional $600 per square foot for interior improvements. This is far greater than the high end of the office spectrum in those same top three markets, where office construction costs range up to $850 per square foot for a new building, plus an additional $110 to $315 per square foot for tenant improvements.

For more information, please see the following sources:

  • Office-to-Lab Conversions Pick Up, Despite Costs
  • Colliers Report
  • Office Building Loans

What are the best practices for office-to-lab conversions?

The best practices for office-to-lab conversions depend on the asset and the type of tenant it is looking to attract. Generally, the most expensive characteristics of lab and life science buildings include emergency power generators, additional plumbing, improved HVAC systems, higher floor load capacities, and increased security requirements.

For financing office-to-lab conversions, there are a variety of loan products available. For example, commercial real estate loans are available for up to 25 years with fixed or variable interest rates. Additionally, SBA loans are available for up to 25 years with fixed interest rates. Lastly, bridge loans are available for up to 24 months with variable interest rates.

What are the potential risks of office-to-lab conversions?

The potential risks of office-to-lab conversions include increased construction and conversion costs, as well as the need for additional plumbing, improved HVAC systems, higher floor load capacities, and increased security requirements. These can all add significant costs, and as a result, new lab space can cost up to $1,200 per square foot to construct, with an additional $600 per square foot for interior improvements. This is far greater than the high end of the office spectrum in those same top three markets, where office construction costs range up to $850 per square foot for a new building, plus an additional $110 to $315 per square foot for tenant improvements.

In this article:
  1. High Demand for Life Science Space Drives Office-to-Lab Conversions
  2. Why Are Life Science Assets Expensive to Build?
  3. The Rental Upside
  4. Related questions
  5. Get Financing
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